Lactate is preferred by lung cancer cells than glucose
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One thought on “Lung cancer cells love lactate”
Breakthroughs on the Cause and Cure of Cancer
I – Stress as the Primary Factor
Carlos ETB Monteiro, “Stress as the Inductive Factor for Increased Lactate Production: The Evolutionary Path to Carcinogenesis”. Positive Health Online, Edition 241, October, 2017 at http://www.positivehealth.com/article/cancer/stress-inductive-factor-for-increased-lactate-production-evolutionary-path-to-carcinogenesis
In the present paper is discussed about the recent evolution in the understanding of the role of lactate formation in promoting cancer.
On it is postulated the hypothesis that chronic stress is the major risk factor and inductor of the increased lactate production which might lead to the carcinogenic process. It also explains how stress develops lactate formation, what was discovered in 1925.
The current hypothesis support ketogenic diets for prevention and therapy for cancer. This inside the reasoning that while fats do not have appreciable effects on the sympathetic nervous system (SNS) or in lactate formation, high carbohydrate diets have significantly effects on both SNS and lactate formation.
At the end of the paper has a short explanation and link to a parallel article where is discussed cardiac glycosides (ex.: digitalis like digoxin) as the fundamental drugs for prevention and treatment of cancer.
II – Cardiac Glycosides (ex.: digitalis like digoxin), as the Fundamental Drugs
Carlos ETB Monteiro, “Cardiac Glycosides at Low Concentration Providing Neuro-Hormonal Effects.: The Final Solution Against Cancer?”. Positive Health Online, Edition 241, October, 2017 at http://www.positivehealth.com/article/cancer/cardiac-glycosides-at-low-concentration-providing-neurohormonal-effects-the-final-solution-against-c
In a central article published in the present edition of this journal was introduced a new hypothesis postulating stress (chronic sympathetic dominance) as the inductive factor for the increased lactate production found in cancer patients.
In it has shown the important role of stress as the major risk factor for cancer, also discussing on how it develops lactate formation. 
In the present article is postulated that cardiac glycosides (digoxin, etc..) at low concentration doses fit perfectly well with the hypothesis of stress as the primary risk factor for cancer being these fundamental drugs for its prevention and therapeutic.
The article also discusses laboratory experimentation and clinical studies using cardiac glycosides. These have shown properties of induction of apoptosis and inhibition of proliferation of cancer cells. This apart of a large reduction in mortality of cancer, in patients taking these drugs at low concentration doses.
It also tells that some cardiac glycosides have shown sympathetic and glycolysis (glucose consumption and lactate) inhibitory effects.
Finally, this article explore the role of endogenous digitalis-like compounds in cancer and in other diseases.